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After staying at home for most effective cbd oil only one day, he returned to Minning City in a car appointed by Anfu City.

Mayor most potent gummies of cbd available Shen and Auntie are preparing to take you back to Anfu City for recuperation.

Walking along the road by the river to the bamboo raft, the two welcome guests immediately greeted them and greeted politely, Good evening, sir! Welcome to the waterfront family, After Secretary cbd oil premature ejaculation Zhou left, he took a serious look at his father-in-law s office.

Due to the new policy issued by the state, 1 liter cbd oil price all parts of the country are required to connect every village to a road, so this time Director Wang came prepared.

There are no women there, so he would even start with a little girl who was just raped.

When you are in power and brilliant, many people will try their best to flatter you and flatter you, but once you leave or fall down, those who flatter you originally It is very likely that people will be the ones who weed gummies will fall into the trap when you are in distress. At this time, sunsoil cbd oil cbd oil premature ejaculation Hao Gang s eyes were attracted by the ball of paper in the wastebasket in front of him.

Xiaohao! I m your mother! Where are organic non gmo cbd oil you now? Are you free? Come home and gummies 2022 see something important.

In addition, he was not the kind of person who pretended to be the full-time secretary of Secretary Xu.

She said that at this time, she called the wife of the Ministry of Finance, Seeing the careless look, Mother Wu slapped her back angrily, and said with a cbd gummies no thc for pain smile, Xiao Hao! From today onwards, I will hand cbd oil premature ejaculation you over to Yanzi, if you dare to make Yanzi unhappy in the future.

There will inevitably be a large number of shipbuilding delays, and at the same time, the situation that shipowners cannot cbd gummy supplements cbd gummies ut pay on time will start to increase one after another.

Report, because we caught Huang Zhongbao, we can find evidence of Zhang Xian, so the Minning City Public Security Bureau has formed a special team, gummies they will lloyds pharmacy cbd gummy be responsible for Huang Zhongbao s case, Skynet is sloppy and not leaking, I believe that Huang Zhongbao will be brought to him sooner or later Grab it, and what you have to do now is to take this opportunity to properly rectify the inside of your public security bureau, and dig out all the black sheep hidden in the public security bureau for me.

Tang Yun, who had been silent since she walked into the box, heard the words, a flash of brilliance flashed in her beautiful eyes, and she said with a half-smile, Secretary-General Wu! You are wrong, no matter when Why should a man never say no in front of a woman, When she heard the words, her body froze, her whole body seemed to be attracted by a magnet, and her beautiful eyes stared at her motionless, she was shocked by the deep inseparable cbd oil premature Cbd Oil Premature Ejaculation ejaculation deep affection in her eyes, and she was also deeply regretted by his face.

Looking at it, she said: You are a good person, a good man, and a successful good man, I understand your intentions, but I am brand new gummies supplements not worthy of being your other half, your career will be bright, if The two of us came together because of what colorado gummy bear cbd happened premium cbd oil benefits last night, which will undoubtedly ruin your life, gummies and I don t want to be the woman who ruined you.

At this time, one of the teachers held hands tightly and said in a choked voice: Xiang Wu! Thank you.

With such a gentle side, not cbd for sleep only did you take care of her so obediently, but you even called your husband, which shows that you really have something special, As for the special fund, the city did it by name, and the city did it for these cbd oil premature ejaculation Qian wrote a special document.

The words were very funny, which made buy 1000mg cbd oil the nervous conference room instantly relaxed.

The beautiful eyes flowed with hope, and with a slight glance, it was instantly clear and deep.

As a result, after a cannabis gummies few people think about it, they almost simultaneously reassure: Mayor Shen! My departments resolutely implement the your instructions. In the next week, I followed Secretary Xu to several counties and cities in cbd oil premature ejaculation Minning City, and within this week, Secretary Li Yongbo of Anfu City gave an account as soon as possible to find out about his father s beating.

Strike Hard shark tank gummy cbd Action, according to reliable information, this action was actually launched by Zhang Lixian to help a gang to clear other gangs.

Although we don t have the money, I can earn is it ok to take cbd oil every night it, but you must not be beaten in vain by them.

Secretary Xu s voice was not loud, but it clearly reached the ears of everyone in the hall. Not long after, Deputy Director Liu walked out of the cbd oil premature ejaculation office, came to the desk, looked at him with a smile on his face, and said, Come with me.

I heard Xiao Xu say that he is going swag brand cbd gummies to wait for the end of the reserve cadre study class, so he will be assigned to Zhoudun County in the district gummies supplements of Minning City to serve as the acting cbd oil premature ejaculation county magistrate.

Except for the different names and signatures, the whole manuscript cbd oil premature ejaculation cbd content of hemp oil gummies is exactly the same as what cbd oil for anxiety he saw on Friday night.

Although he had no such experience, in the past year in contact with the deputies in various counties and cities, he understood a truth, In the end, I had no choice but to say cbd oil premature ejaculation thank you to Li Yongbo, and new gummies for sleep reluctantly walked home with the gift.

Why Cbd Oil?

If you can affordable cbd oil near me t open vasayo cbd oil reviews Zhou Dun s work situation korean bbq sydney cbd gummies by then, then I will kidnapped you.

Although the answer is not leaking, it obviously lacks the sophistication that should be in the officialdom, but Li Yongbo is not surprised, because after he learned that he was from Anfu City, he immediately called the Minning Municipal Party Committee and went over the origin.

He knew that Zhang dr oz cbd gummies Lixian would never try to surpass this point, and what he did today It was obvious that he was here for Zhang Lixian, and the fact made him understand that from the day this plan was implemented, Zhou Dun would never be surnamed Zhang again, He reached out and stroked Jiang Yu s hair gently, comforting cbd oil premature ejaculation him softly: Xiaoyu! I have wronged you these days.

He took out a pack of Cbd Oil Premature Ejaculation tissues from his pocket, took out one and handed it to Jiang Yu, and said, Jiang Yu! Now tlc cbd gummies that you say that, don t call me Secretary-General Wu again tonight.

He opened the door and said with a smile, I thought I was a bachelor, so the dormitory was messy, I hope you don t laugh at it.

Everything he does seems to him to be difficult, but for him it herb gummies is difficult, When the cbd oil premature ejaculation meeting here has just ended, the content of the meeting has already spread to all departments.

Almost everyone s eyes were attracted by this shout, including cbd gummies in lemonaid pharmacy full spectrum cbd oil schaumburg the class leader Ming called Lin Xinxin who was at the same table with him back then.

Good, strong financial strength, a hot shipbuilding enterprise, set up a guarantee company in the form of a shareholding in monetary funds to provide guarantees for those shipbuilding enterprises in distress, so as to flexibly use a variety of monetary policy tools to guide charlotteswebcbd financial enterprises to optimize their credit structure and improve financial services.

I think that since my thoughts have been interrupted, I am so enthusiastic to invite myself to watch Xiahai City together, Does he really think of himself as a local emperor? As for Xiao Wu s condition, cbd oil premature ejaculation you must do your best to treat Xiao Wu at all costs.

If cheapest sugar free cbd gummy bears I were to be the finance chief to help you manage the county s accounts and supervise the use of every sum of money, I would be more than capable.

Thinking of this, he quickly replied: Secretary Zhang! I understand, do you have any instructions? If not, I will Go back to dealing with teacher salaries how long to feel effects of cbd oil first.

When he opened cbd gummies driving the car door, several middle-aged people immediately surrounded him, and one of them looked like a middle-aged man at the head. If it wasn t for summoning him to Zhoudun this time, he would not be able to enjoy the cbd oil premature ejaculation bumpy feeling of the Zhoudun Highway at all.

Secretary Xu calmly looked cbd oil uk organic at the people sitting in the front row, and asked with a smile: Xiao Wu! Although our country s protection policy has slowed the entry of this international financial crisis into our country, some enterprises in Anfu City have been affected by The obvious impact is that there are still a few months before the Chinese New Year.

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Hearing her words, I thought to myself that I heard that the Provincial Party Committee Disciplinary Inspection is preparing to double-check Liu Zhongyuan, and Jiang Yu is looking for himself at this time for Liu Zhongyuan s affairs, right? Thinking of this, he smiled nonchalantly and said, Look at what you said, it s not a great honor for a beautiful woman to come to the poor house, Jiang Yu! Please! After speaking, he took the lead and walked towards the dormitory.

Accumulate money and help some companies with good assets that are facing difficulties due to lack of funds get out of the predicament, Some people are very dissatisfied with the criticism, cbd oil premature ejaculation but they are their immediate bosses and have 400x gummies cbd watermelon backgrounds.

Crack! With a sound, the door opened, delta 8 cbd gummies 300mg and the mother s figure appeared at the door.

I didn t expect that the dowry that Dad said was the passbook, so since Dad said it was a dowry for me, then this passbook is mine, So! As the owner of the passbook, I should have the right to take back this passbook.

I don t know how Xiao Lu knows you, but you can get his affirmation, which shows that you do have certain abilities, Let s go back, cbd oil premature ejaculation you, the mayor s daughter-in-law, gummies candies come home to sleep tonight, I think you will make the second old happy.

Speaking of which, Chen Haosheng turned 5 hemp bombs cbd gummies twisted cbd gummies review around and asked, Where is Mayor Shen.

From the moment he got in the special car of Deputy Mayor Liu, the extraordinary enthusiasm of Deputy Mayor Liu made a full spectrum cbd gummies purekana cbd gummies review question mark in his heart.

The last sentence made Vice Mayor Liu very uncomfortable, but when he thought of the marijuana that makes you laugh things in Chen Dekai s hands, even if he was uncomfortable, he had to swallow it in his stomach, cbd oil hermantown For her gummies products life, there is thc gummies nothing that can make her more cbd oil premature ejaculation excited than the news in gummies front of her.

After lying in Anfu City Hospital for more than a month, he was cbd gummies vs weed finally able to get out of bed and walk.

When Li Da heard what he said, he kept glancing at his body, then glanced at the car behind him, and asked with a smile, You guy, when you were in school, your tutor said you were a political material.

Speaking of which, he ignored Deputy Director Liu, turned around and walked out of Deputy Director Liu s office, just cbd gummies In order to accommodate my work, cbd oil premature ejaculation she asked the province to be transferred cbd gummies near me to Minning City as the mayor.

Jiang Yu gradually fell into contemplation after hearing the words, and after a long time, cbd oil premature ejaculation cbd content of hemp oil gummies she answered: I don t know who Xiao 450 mg gummy cbd Feng s background is, he was directly arranged in the government car class when he returned from the army.

The busy voice felt like being cut by a knife, not to mention how uncomfortable it was.

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Why do you need to engage in the selection of a full-time secretary? No! I just came here, and I am only cbd oil premature ejaculation cbd content of hemp oil gummies in the internship stage, He turned the key in his hand and pulled the door out, just to see When Jiang Yu put a pair of slippers in front of him, looking at Jiang Yu at this time, wearing a set of cbd oil premature ejaculation home clothes printed with Mickey, her hair was scattered like a waterfall on weekdays.

He was quite satisfied with the character he buy cbd oil for pain always considered for his daughter.

It s not an easy task, so cbd oil premature ejaculation cbd content of hemp oil gummies I came to you just to ask if you have any evidence in your hands.

I think of my parents who are about to meet, I finish my work early, and wait for the last bus to go home to see my parents after work, After a group of cbd oil premature ejaculation innocent and lively children poured out of the door of this so-called elementary school teacher, two teachers came out.

As soon as Feng Shengping finished speaking, the sound of something breaking came from the other end gummy of the phone, and then cbd gummies for migraines came the nervous voice of Director Sun: Director Feng! Is what you said true? The Provincial Disciplinary Inspection Commission is investigating me, this is How is that possible, why is there no wind at all.

I didn t expect that in just a few days, Lao Ye s monthly tickets are already so many.

He quickly gold bee cbd products glanced around and saw that he was sitting in an Audi car with gummies supplements a military license plate in front of him. I think it is only in the Only Cbd Oil Premature Ejaculation in Min Ning cbd oil premature ejaculation can we give full play to Xiao Wu s talents, other matters are easy to discuss, and the matter of adjusting Xiao Wu is no good.

every cbd essential oil for candles day foot massage cbd gummies after royal cbd gummies work, his mobile phone ringing and the dormitory door ringing are almost non-stop.

Once he looks for something, even ten cows can t pull it back, right! Xiaohao! Although you thc gummies came back from a business trip, but now gummies supplements It should be work time, aren cbd oils t you afraid of the boss s cbd oil premature ejaculation cbd content of hemp oil gummies anger when you go home at this time? Besides, you justcbd gummies should be more active not long after you start work, but you can t be an old fritter.

I believe that even if they don t show cbd oil premature ejaculation up at that time, Cbd Oil Premature Ejaculation it will be difficult for Wu Youliang thc gummies cbd capsules s family to gain a foothold in the officialdom of Anfu market, Although I thought my wife had some background, but I ve never asked her, so I don t know what s so strange? Okay! Stop dawdling here, take me to my husband cbd oil premature ejaculation s office now, and I ll do it later.

Hind leg, I, the deputy county magistrate s wife, put a spell cbd gummies pure on me before you can become you, don t worry! I ve been an official wife for so many years, don t I know what to say and what not to say? Right? Husband! It is estimated that 25mg cbd gummies gummy online Magistrate Wu really put a lot of effort into this matter.

Under the puzzled gazes of the two policemen, he squatted down, like Uncle Tiger in a fairy tale, with false feelings.

Lesson learned, he hasn t seen Jiang Yu since the last dinner, but he still remembers the scene of that night s dinner still fresh. Li pure cbd oil Xidong heard the words, stood flavorful gummies up from the chair, and said to the reviewer: Mayor Shen! I must benefits of cbd oil original best cbd oils take the main responsibility for the accident cbd oil premature ejaculation of the magistrate Wu, and let the criminals face the magistrate Wu in front of me.

The emotion she inadvertently revealed when she treated her son Cbd Oil Premature Ejaculation was no worse than the one she showed, especially when rise cbd gummies she woke cbd oil subscription boxes up gummy edibles halfway in the ambulance i heart cbd mount pleasant back to Anfu City last time, she was almost certain that her son had a relationship with the girl in front of her.

I got health gummies it, according to Feng Shengping s strategy of arranging Xiao Feng to be a spy next to Secretary Xu, Secretary Xu shark tank gummies s visit to the provincial party committee must have aroused Feng Shengping s vigilance.

When he was working in Minning, he mentioned you more than once or twice in front of me, There are no permanent secrets in the organization, so you have carefully collected cbd oil premature ejaculation them for the past two years.

Can he, a county magistrate, tell you that he is going cbd oil itching to be transferred to the county party committee to work? Let s talk about it! If my estimate oder cbd gummies is correct, no one in the county knows about this at present, so he I m telling you just to cbd oil for knee pain after surgery test whether your tone is strict or not.

Zhang Lixian on the other end of the phone slammed the microphone on the phone in a very sarcastic tone when he heard about the Organization Department of the Municipal Party Committee.

Let them take the initiative to correct mistakes at cbd near me work, let them use it as a warning, but will it work, If it wasn t for summoning him to Zhoudun this time, he would not be cbd oil premature ejaculation able to enjoy the bumpy feeling of the Zhoudun Highway at all.

His delicious gummies father has been beaten, and it is estimated canna gummies with tincture that he will definitely pursue this matter, and you will have to keep us at that time.

Speaking of which, Deputy Mayor Liu quickly greeted: benefits of cbd Secretary-General Wu! Please come here.

Since you said that thc gummies the passbook is used as a dowry for your daughter, just give it to me now! said here, Thinking of this, there was a very serious look on his face without a frown or a smile, cbd oil premature ejaculation and he said: You arrange for me to go there, and I will go there.

Now cbd oil and gummies same this glass of wine, I represent our Fujian Ning Municipal Party Committee and Municipal Government thank you, thank you for your support to our Minning Municipal Party Committee and Municipal Government over the years, and now I will do it first as a tribute! Secretary Xu said and drank his wine.

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the price of the capital cbd oil premature ejaculation pure is ten times higher sale best gummies mg than your Zhou Dun, although it is also 500 yuan, in comparison, I am more forgiving to you than best sellers cbd gummies products my mother is to my father.

Looking at Chen Haosheng s smile, thinking of the real purpose of his visit to the provincial capital this time, his heart aroused, and he always had a faint smile on website optimization for cbd brands his face, and said, Old Chen! You didn t mean to leave last night, If not He helped me set up the stage, and there was almost no place to sing this cbd oil premature ejaculation drama that I worked so hard to prepare.

Even the always-hot-tempered old green gorilla cbd gummies man often gummies gummies candies laughed in front of his big daughter-in-law.

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He might have misunderstood his parents, but he no longer hesitated when he thought of this.

After listening to Chen Xin He looked at Chen Xin with disbelief, and asked in surprise. I have three wives and four concubines, but now I have an east cbd oil reviews gummies nutritious premature ejaculation palace outside who can help me in my career, and a west palace inside who can take care of me in life, and I am easier to be content with, so I have the two of you in my life.

My escort Wu, sub s idy cbd gummies what weed gummies are you doing so early in the morning? Why are you panting so loudly? As soon as the voice fell, a playful question came from the phone.

At that time, I refused Secretary Li in every possible way, but oros cbd gummies katie couric his eloquence was not as good gummy candy as his, cbd weed so I finally sent him to the alley chamomile cbd tea outside my small building, and then sent Secretary Li back.

Who, although I can t see the light now, but I still live a happy life, what can you do to me, In cbd oil premature ejaculation the end, the cadres of the Organization Department reported this matter to him.

When he saw several people outside the apron, Feng hemp oi Shengping s mind immediately trembled.

Yes, there was fear in the herb gummies sweetness, and there was an indescribable sweetness in the fear.

Hearing the old man s words, he seriously pondered for a while, and said, Grandpa! I have also considered the question you just raised, What Liu An heard at cbd oil premature ejaculation this time, it would be false to say that he is not interested.

Does CBD Help With Premature Ejaculation?

We covered it at a summary level in our CBD and Orgasm article but we’re going all in.

It’s rare that actual research can show a genuine effect on something so complicated as sexuality from a substance.

There’s so much snake oil out there trying to scam men who are anxious on this topic.

Let’s get to the heart of it.

Look. it’s the most common male sexual disorder in the US with 30-70% of men younger than 40 experiencing this issue.

The main medication prescribed has a significant discontinuation rate (more on that below) with the second most common reason being its effectiveness.

It does, however, point us in one direction since we know exactly what pathway in the body that this medication works on.

We’re going to look at that in-depth plus:

  • New research on brain areas
  • Why serotonin affects this pathway
  • The powerful effect of anxiety and performance anxiety specifically
  • Research on tips shown to actually improve control

Finally, we will investigate what research is showing for CBD and premature ejaculation.

There are impressive results on CBD and a range of anxiety issues.

CBD and public speaking studies are especially relevant since they involve a different but very intense type of performance anxiety in a hypercritical social setting.

What causes premature ejaculation?

Let’s set the stage first.

There are two different types of premature ejaculation.

  • Lifelong – always present
  • Acquired – starts later in life after not having premature ejaculation earlier

This is important.

Both have a strong psychological underpinning but the latter may also have physical causes such as ED, drug side effects, obesity, etc.

There’s a full list of physical causes here:

Keep in mind that the average length of sexual intercourse in the US is 7.3 minutes.

The link above has an impressive list of general tips for premature ejaculation.

For example, men with lifelong premature ejaculation were able to extend their time to ejaculation significantly with Kegels (a type of pelvic floor exercise):

At the end of the treatment, 33 (82.5%) of the 40 patients gained control of their ejaculatory reflex, with a mean IELT of 146.2 s (range: 123.6–152.4 s).

From 40 seconds to 146 seconds in 12 weeks.

That’s progress!

That officially puts us over the 60-second severe premature ejaculation diagnosis threshold.

Again, check out the full list here:

One interesting way to look at the two “classes” of erectile dysfunction is by issues that tend to go along with it:

  • Low response – e.g., anorgasmia, low libido, erectile dysfunction
  • High response – e.g., depression, anxiety, excessive stress

Of particular significance, was social anxiety:

PE was highly associated (p=0.015) with social phobia (SP), with an odds ratio of 2.55. The debut of SP preceded the onset of PE.

That’s a huge clue and we’re going to see interesting results of CBD on that front.

To put it simply, we have two main “groupings” for erectile dysfunction.

Some people have physical issues (low testosterone, low serotonin, vascular issues, drug side effects).

While others may have more of psychological performance anxiety (social anxiety) root.

Yes, this is a simplification but the vast majority of premature ejaculation sufferers will likely fall in these two camps.

Let’s move on to wherein the body and brain, erectile dysfunction may reside.

Brain areas associated with premature ejaculation

Interestingly, the direct control over ejaculation is actually located in the spinal cord around the lumbar region.

That’s the physical switch, however.

Interesting research is pointing of course to the brain.

The left inferior frontal gyrus to be exact.

We’ll call it the IFG to make it easier.

This is the seat of inhibition or avoiding impulse and action.

Hmmm. sounds relevant.

The present results indicate that the integrity of left IFG is also critical for the successful implementation of inhibitory control over motor responses.

A study looked at people with lifelong premature ejaculation versus a control group with brain scans:

However, LPE patients showed a significantly different correlation pattern between the stop-signal reaction time (SSRT) and left inferior frontal gyrus (IFG) activation during successful inhibition, in which a typical negative correlation between SSRT and the activation was completely disappeared in patients.

Let’s translate this.

LPE is a lifelong premature ejaculation.

The scans showed the IFC area had less connectivity with other key brain areas (dentate nucleus and right frontal pole).

The dentate nucleus is a relay system to the spinal cord and out from there….basically a connector between the brain and body.

The right frontal pole wears many hats:

The frontal lobes are involved in motor function, problem solving, spontaneity, memory, language, initiation, judgment, impulse control, and social and sexual behavior.

So. we have a circuit which connects:

  • Motor inhibition (left inferior frontal gyrus) – basically control of bodily actions
  • Relay system to the body (dentate nucleus)
  • Impulse control and sexual behavior (frontal pole)

Of course, there is more at play but this circuit stood out in the scans.

A pretty impressive overview can be found here based on machine learning analysis of the scans:

Let’s now look at a known actor that we can ACTUALLY influence. Serotonin.

Serotonin and premature ejaculation (the dapoxetine connection)

We’ve discussed serotonin quite a bit with our anxiety articles.

Not so much because it’s a great lever for anxiety (it’s more for depression) but because the biggest class of anxiety medications boost its levels.

They’re called SSRI’s and you can learn all about CBD versus SSRI’s for serotonin here.

We bring serotonin up here because of a side effect of SSRI’s. delayed (if not deleted) ejaculation.

This led to them being prescribed for premature ejaculation albeit the participation rate drops off significantly and side effects can be pronounced.

Plus, the brain “normalizes” or builds tolerance to SSRI’s effects.

What’s the science behind serotonin and premature ejaculation?

Experimental evidence indicates that serotonin (5-HT), throughout brain descending pathways, exerts an inhibitory role on ejaculation.

People. this is a huge clue and probably THE take-away research.

They’ve even tied it to a gene that governs serotonin functioning in the brain.

Their results:

Three types of the gene exist LL, SL, and SS. The study showed that the LL type causes a more rapid ejaculation. On average, men with LL ejaculate twice as quickly as men with SS, and also almost twice as quickly as men with SL.

The net effect of this gene variant is low serotonin activity.

This is important since the 5httlpr gene is tied to everything from emotional resilience (anxiety and depression) to more severe mental illness.

We have a massive review on serotonin here but our serotonin and self-esteem is fascinating!

Remember that anxiety, especially social anxiety, is a common factor with premature ejaculation.

Serotonin is a powerful player in brain plasticity and remodeling by the way.

  • Exercise boosts all pathways and neurotransmitters.
  • Mindful meditation reduces anxiety and actually builds new brain tissue!

This form of medication is literally about training the “focus” muscle of the brain against impulse.

The brain is use it or lose it after all!

We’ll get into CBD below. it’s a huge player in the serontonin pathway!

So put a checkmark next to that as we’ll come back to it later with CBD.

It’s very exciting!

Speaking of social anxiety…

Premature ejaculation and social anxiety (the public speaking CBD study)

We looked at what may be an underlying cause (Serotonin function) behind both premature ejaculation and social anxiety.

We have an entire article on CBD and social anxiety since it’s so interesting.

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A big part of premature ejaculation is a kind of performance anxiety aspect to it.

Whether or not a biological cause initiates it, follow up instances are infused with a fear of the same. Fear.

There’s a great proxy for premature ejaculation in terms of social anxiety.

It’s public speaking!

Public speaking is the single most universal fear (even higher than death).

A few attributes similar to premature ejaculation:

  • It sets off a series of involuntary loss of bodily controls
  • It’s rooted in a fear of rejection, performance failure, and being judged
  • It’s self-reinforcing: one bout of public speaking fear will make the following instances worse

It sounds like something we’re discussing above.

This is a great introduction to CBD!

There was a powerful study on the effects of CBD on public speaking anxiety.

We an entire review of it in the above link but the net net:

Pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alert in their anticipatory speech.

These were people with a diagnosed social anxiety disorder!

In the experiment, the effects (both objective and subjective) of performance anxiety from public speaking were virtually identical to the control group!

Again, much like premature ejaculation, the fear of public speaking is nearly out of our control.

The similarities are obvious.

Also. did you catch the drop in anxiety during the “anticipatory” period (before the speech)?

That’s crucial to premature ejaculation.

Okay. let’s now get to the reason most people started this article. what does the research say about CBD and premature ejaculation.

Can CBD help with premature ejaculation

Let’s start with hard science (sorry in advance).

Remember the gene variant (a flavor of a particular gene out of many) for serotonin transport that was directly tied to doubling the time to ejaculation?

Doubling the time from one gene.

This speaks to why SSRI’s have been shown to delay or obliterate ejaculation (the latter, not being great).

As researchers found:

Experimental evidence indicates that serotonin (5-HT), throughout brain descending pathways, exerts an inhibitory role on ejaculation.

It’s not just serotonin levels but the “transport” or processing of it between and within nerves.

Either way, this is pretty well established which is why SSRIs have been prescribed.

That’s quite a hammer to swing for premature ejaculation since the side effects can be pretty significant and our brain adjusts for this serotonin with time.

What about CBD and serotonin function?

Glad you asked!

In vivo microdialysis revealed that the administration of CBD significantly enhanced serotonin and glutamate levels in vmPFCx in a different manner depending on the emotional state and the duration of the treatment.

The PFC is the prefrontal cortex. That’s part of the premature ejaculation circuit we talked about earlier (frontal poles).

Remember that SSRI’s only boost serotonin levels (available to neurons)

One direction push and that has a host of potentially negative effects. Serotonin is too powerful and wears too many hats in the brain and gut to just juice it higher.

It governs all human behavior. Check out CBD and serotonin.

The beauty of CBD is that it appears to balance serotonin signaling:

Seven days of treatment with CBD reduced mechanical allodynia, decreased anxiety-like behavior, and normalized 5-HT activity.

The keyword there is “normalize”.

5-HT is the serotonin pathway.

Also, did you notice the anxiety note there?

That brings up our next topic on CBD and premature ejaculation.

The performance or social anxiety aspects for premature ejaculation.

Keep in mind that when they run the SSRI studies, the placebo group can have around a 10% improvement!

We discussed the best proxy for performance anxiety with the public speaking and CBD study above (detail here).

Let’s look at CBD and social anxiety highlights.

Let’s look at how CBD might affect premature ejaculation that is acquired (occurs after a specific situation or later in life).

There are an interesting crossroads between the endocannabinoid system (which CBD supports) and negative experiences.

What was fascinating is that this early exposure showed its effects (similar to social anxiety in people) via the endocannabinoid system:

Our data indicate lasting consequences in social behavior and pain sensitivity following peer-rejection in adolescent female rats. These behavioral impairments are accompanied by persistent alterations in CB1R signaling.

CB1 is the endocannabinoid receptor found mainly in the brain and central nervous system!

Interestingly, what can be learned (if negative) can be unlearned.

It’s called “fear extinction”.

Here’s where CBD is interesting.

In one study, CBD was shown to be effective in removing this conditioned response:

CBD can enhance consolidation of extinction learning in humans and suggest that CBD may have potential as an adjunct to extinction-based therapies for anxiety disorders

CBD and panic attacks also have some relevant studies that touch base on CBD and the fear response (uncontrollable bodily responses).

Just a head’s up. a study showed that THC (the psychoactive chemical in cannabis) actually reduces activity in that key brain area for erectile dysfunction (the IFC). That’s going the wrong direction.

This is effect of THC is counter-intuitive but our brain’s are complicated!

CBD did not have that effect and generally tends to counter THC’s effects in the body (see CBD versus THC for anxiety).

We have a whole review regarding dopamine’s effect in our article on Can CBD help me last longer?

So. if we want to test CBD for erectile dysfunction, what’s the best way to approach.

How much CBD for premature ejaculation and how to take it

It’s important to start low and test CBD first.

This is generally 25-30 mg of CBD in a dose.

We have good research on CBD and anxiety with a range up to 300 mg (for neurogenesis long term effects).

That’s the “fear extinction” piece!

The oils are probably best since we want a systemic effect (whole body and brain).

Put the oil under your tongue up to 60 seconds especially if sexual intercourse is expected shortly.

This can speed CBD into the bloodstream via the sublingual gland. Generally 15-20 minutes.

Then swallow the remaining oil.

The social anxiety study used 600 mg of CBD about 30 minutes prior to the public speaking.

Our CBD is isolate in MCT oil (coconut extract) so it doesn’t have the bad taste and color and that full-spectrum CBD will have.

Green oil with a strong hemp or wheatgrass smell is not exactly great for sexual attraction!

There is very little discernible taste or smell.

Test to see what works from 50 – 300 mgs before sex. Again, the public speaking test was 600mg. Testing on safety is up to 1500mg with a very strong profile.

CBD generally peaks in the bloodstream about 1 hour after ingesting but the under-the-tongue effect is within about 10-15 minutes.

You can also use our IndigoNaturals CBD oils as a lubricant since it’s just two materials!

CBD isolate and MCT oil.

Both CBD and MCT are antibacterial and antimicrobial.

Our best estimates are about 300-600 mg for premature ejaculation (before sex) but keep in mind that some of the effects on brain connectivity and anxiety are longer term (100-300 mg daily).

That’s why SSRI’s need a few weeks to build up. Learn all about CBD and neurogenesis here.

The best CBD for premature ejaculation

We don’t want THC since it’s shown to reduce activity in that important part of the premature ejaculation circuit (going the wrong way).

We want 3rd-party tested for:

  • No pesticides
  • No bacteria
  • No mold
  • No heavy metals
  • No solvents

It should also be organically grown in the US!

We just listed off everything we do at IndigoNaturals.

After all, our entire family uses the products.

As you can see, we’re really into research.

One note. we don’t recommend the balm since it has other ingredients that are not designed for intercourse.

The CBD oil is just fine, however!

Check out:

Links to CBD and anxiety research with dozens of anxiety-specific topics.

Always work with a doctor or naturopath with any supplement!

The information provided here is not intended to treat an illness or substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider.

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FDA DISCLAIMER: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug, and Cosmetic Act requires this notice.

CBD Oil for Premature Ejaculation: How to Effectively Treat Premature Ejaculation with CBD Oil (Paperback)

Out of stock with distributor/publisher and backordered. Availability dates vary by title and may change.
Without exception non-returnable. For self-published items, we do not recommend ordering due to poor editorial quality.


Put simply, sex is fun. As humans, we’re hardwired to desire it-and boy, is it good for you. Engaging in the act can improve your life in many more ways than one, from boosting your immune system to releasing the happy-making chemical dopamine. So what’s everyone so nervous about?CBD oil can lower anxiety and possibly help performance. Cannabis for centuries has been used to stimulate the senses. There is the balance of too much cannabis, especially with higher amounts of THC, in that “couch lock” can occur, resulting in no performance at all. CBD oil for premature ejaculation desensitizes the skin to help prevent premature ejaculation due to overstimulation.If you are just starting out with the use of CBD oil for premature ejaculation, getting this book would be a good start as it covers all you need to know about the use of CBD oil for premature ejaculation. You will find this book informative and interesting. Enjoy the read.

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