CBD Vape Oil Side Effects

What Are The CBD Vape Side Effects – Are There Any To Lose Sleep Over? We Have Gone Back Over Updated For 2022 Studies To Bring You The Lowdown. The problem many CBD vapers have faced recently seems to stem mainly from poor regulation over the vaping market in general, and the subsequent unreliable quality of any vape or vape oil. There are Benefits and Side Effects of Vaping CBD. Today, Spinfuel VAPE takes a look at both. Before deciding, read this in-depth primer.

CBD Vape Side Effects | Is Vaping CBD Safe?

I’m David, co-founder of Vaperun and Vape & Juice I’ve got pretty extensive experience in the vaping industry. I run a Retail Podcast. Responsible for stealing the company’s stock of 6mg Heisenberg and stroker of cats. Find me on LinkedIn

Note: This CBD Vape Side Effects Post has been co-authored by Dr Andres Maldonado M.D., in line with the ‘Vape and Juice Medical Review Policy’. Evidence based reporting.

CBD vape side effects are something you will probably find yourself researching either before you try your CBD vape juice for the first time.

CBD comes from the cannabis plant, which might have you thinking about negative ways it may make you feel. As, after all, cannabis containing THC is illegal because of its side effects.

Here’s a short video on what CBD is, just as a refresher:

However, CBD doesn’t contain enough THC in the slightest, if at all, to have any intoxicating effects. In this article, we will take you through the following topics.

If you’re in a rush, skip ahead with the links below

We don’t want to teach you to suck eggs, so we will keep it brief on what CBD is and if you want more info then head over to History of CBD to find out more.

CBD vape side effects

Vaping CBD does have some side effects, which is, of course, the reason why you might take it! That said, there has not been a huge number of studies run on humans, and most have been done on animals or in vitro conditions.

To get a fuller picture of adverse effects on vaping CBD, more research will need to be done, similar to the work listed below.

Some of the most well known and researched CBD side effects include

When taken in larger doses, CBD may make you feel sleepy. This is ideal if you are struggling with sleep issues and want to fall asleep and stay asleep for the night. Research suggests you need around 160mg if you are suffering from insomnia.

In the CBD Study listed at PubMed, when evaluating the effect of CBD vs. placebo in patients with neurodegenerative disease, they found a higher incidence of sedation in patients receiving CBD. Evidence that one should be careful if operating heavy machinery or other equipment when using CBD.

Stay with us, this isn’t a typo or a contradiction. CBD has been found to actually make you feel more alert when taken in small doses. A study on CBD and memory was conducted by Colorado State University, but it is early days and a lot more needs to show in research to suggest at a clinical level, CBD will transform your memory. The brain is still one of the most unknown organs in the human body

CBD has been found to indirectly lower activity in the amygdala which plays a big part in our emotions. This may reduce anxiety and give you a sense of calm. If you are interested in reading further about CBD and anxiety read Does CBD vape help anxiety.

This guidance on CBD and anxiety was more recently hypothesised by running a test on 24 sufferers of societal anxiety disorder, alongside a placebo. You can read the source below – but the findings were that cannabidiol consumption lowered society anxiety feelings on a 100 point scale compared to the test alternative

  • Pain relief and anti-inflammatory properties

CBD is thought to block and bind to receptors. This interaction then changes the way in which we perceive pain. Whether it is headaches, period pains, joint pain or anything in between.

  • Reduction in seizures

There is quite a bit of evidence to suggest that CBD may help those who suffer from epilepsy. There is even a pharmaceutical product which contains the cannabinoid from GW Pharma in the UK. This product is known as Epidiolex and was amongst one of the first of it’s kind in the world.

Negative side effects of vaping CBD

At the time of writing this article, there haven’t been any reports of vaping CBD being toxic. THC on the other hand is. You can read all about the dangers of vaping THC on our post about Dank Vapes.

The most frequently reported side effects of vaping CBD include the following adverse effects.

This data is taken from Medscape which is owned by WebMD and offers access to ongoing medical information and education for professionals. It gives our data the authority it requires, to ensure you are reading credible information.

  • Infections, all (40-41%)
  • Somnolence (23-25%)
  • Infection, other (21-25%)
  • Decreased appetite (16-22%)
  • Diarrhea (9-20%)
  • Transaminases elevated (8-16%)
  • Rash (7-13%)
  • Fatigue, malaise, asthenia (11-12%)
  • Infection, viral (7-11%)
  • Insomnia (5-11%)

CBD and side effects on the liver

If you have a liver disease then you may need a lower dose of the cannabinoid to those with healthy and fully functioning livers. There is a rare side effect of liver injury from taking too much CBD.

It is general guidance that you would seek professional medical advice before taking anything that can disrupt liver function, or alter it potentially in any way. Particularly if you suffer from any liver related issues.

Is vaping CBD safe?

CBD is a non-toxic substance that will not make you feel ‘high’ or intoxicated or any of the feelings you may associate with smoking cannabis.

To make sure you are getting a safe product that actually is CBD, make sure you ask to see a certificate of analysis if it is not obviously available. This will show you everything you need to know about the vape product, so you can rest assured you are getting something that is safe.

You also need to make sure you are taking CBD correctly.

When vaping the cannabinoid you should be using CBD vape juice, not CBD oil. It is sometimes called vape oil, which is confusing. Just remember never to put oil in your vape kit. It isn’t designed to move through your device or your lungs for that matter.

  • Read more on CBD Vape Benefits Next.

Can I give CBD to my child?

Vaping CBD isn’t suitable for children. Nor is vaping itself.

There has been some research into CBD for ADHD and autism as well as anxiety. Many parents have given it to their children – we make no apologies for not wishing to report with an answer to the question: “Can I give CBD to my child.”.

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We as a business stress that our guidance from our Medical Review Team is as follows:

There is very little evidence at this stage to support the use of CBD in children and it is inadvisable to recommend giving CBD to children who’s brains are still developing.

Dr Andres Maldonado M.D.

Can you vape CBD if you are pregnant or breastfeeding

It is advised that you do not vape CBD if you are pregnant or breastfeeding. While it is likely safe, some products may contain other ingredients which could harm the baby. Best to be of the safe side and avoid it until you have had the baby and they are weaned.

CBD and medication interactions

Vaping CBD is generally seen as a safe remedy. However, there is one thing to consider when it comes to taking CBD and that is interactions with medications.

The interactions may change the way the body processes and metabolize certain meds.

Let’s get into a little biology. In the human body – the liver specifically, there are a group of enzymes called cytochrome P450, also known as CYP450. These convert foreign substances to allow them to be eliminated.

Some meds and remedies affect this family of enzymes by either slowing or speeding up the metabolism of drugs. This can then alter how your body processes these drugs or supplements.

These enzymes are also the ones that metabolise cannabinoids, such as CBD. However, during the metabolisation process, the CBD can infer with CYP3A4.

So how can CBD vape affect medications?

So, the CYP3A4 is the enzyme which metabolises lots of the prescription meds out there. If CBD is interfering and inhibiting this enzyme then it can’t do its job of metabolising the drugs as it may have without CBD in your system.

For one example, if your body starts to metabolise your meds slower than its usual rate, then you could end up with more in your system at one time. Giving you some unwanted side effects.

One suggestion is to look for the grapefruit warning. If your medication has a warning against eating or drinking grapefruits while taking it, then CBD may also not be safe. This is because grapefruits inhibit the CYP3A4 like CBD is thought to.

It is important to check with your healthcare provider if you are taking medications and also want to try CBD.


Another such example, is to imagine that a person is taking contraceptive medication and that they start taking CBD. This CBD interaction through reasons at the time unknown, causes a decrease in the effects of the contraceptive and the woman becomes pregnant. This would be a significant problem if you weren’t planning it.

It must be said, this is not a factual scenario and is only to illustrate a point.

What conditions may CBD vape help with?

There are a number of conditions that have shown promise in CBD studies. Some of the studies are in their early research phases. These conditions include:

* From Tourettes, to Multiple Sclerosis, to Neurogenerative diseases, many more things could be added over time – BUT and this is the critical factor, there just isn’t YET the conclusive research to state CBD vaping is the be all and end all.

Despite this, the application of CBD in many diseases is being studied and at length. Maybe in 10 years it could be used for diseases we never even imagined

CBD vape side effects, final thoughts

There are side effects to basically everything, even eating Marmite (heartburn for me). The side effects of vaping CBD are very minimal and don’t happen for everyone. The main concern is to check whether they interfere with any medication you are on by chatting with your doctor or alternative health practitioner.

Everything We Know About the Health Risks of Vaping CBD

The problem many CBD vapers have faced recently seems to stem mainly from poor regulation over the vaping market in general, and the subsequent unreliable quality of any vape or vape oil.

Earlier this year, the United States Army issued a public health warning after medical centers at two bases in North Carolina saw some 60 patients within a few months for health issues that officials linked to their use of CBD vape oils. The symptoms included everything from headaches, nausea, and vomiting to disorientation, agitation, and seizures.

A few months later, North Carolina health officials issued their own warning after local emergency rooms saw some 30 people come in suffering from hallucinations, loss of consciousness, and heart irregularities linked to vaping CBD products. Both notices hinted that officials feared such visits could grow exponentially more common as popular interest in and access to CBD vaping, a legal practice in many states with a host of purported (but still not conclusively proven) health benefits expands.

These reports should be enough to give anyone vaping CBD—or considering it for medicinal or recreational purposes—severe pause. Experts and existing evidence largely agree, though, that CBD itself, even when vaped, is largely safe. But that is only if you can get your hands on unadulterated CBD tinctures to vape. The problem many CBD vapers have faced recently seems to stem mainly from poor regulation over the vaping market in general, and the subsequent unreliable quality of any vape or vape oil.

What are the benefits and side effects of vaping CBD?

CBD is an abbreviation for cannabidiol, one of more than 100 active cannabinoid components found in cannabis. Studies of its myriad potential medical benefits have found that people can tolerate a wide range of doses of it with minimal effects, including weeks on continuously high dosages. Granted, that doesn’t mean there are no side effects. Studies have found that CBD can cause some users to experience irritability, lethargy, reduced appetite or urination, gastrointestinal distress, rashes, breathing issues, or in the worst instances, liver problems or exacerbations of mental health issues.

Knowledge of the way our bodies process CBD also suggests that it interacts with enzymes in the liver in ways that may change the efficacy of a number of other drugs, from blood thinners to anticonvulsants, to antidepressants. This may potentially lead to increased side effects, or even a risk of unintentional overdose on other drugs in the worst cases.

We do not yet know enough to say definitively how common these side effects are, or how many of them are native to CBD usage versus the result of those potential interactions between CBD and other drugs. We also don’t know with any reliability how different doses might lead to different side effects or drug-drug interactions, or how drastically these effects may differ from body to body or in conjunction with other conditions. Nor do we have any good data on how CBD might affect children differently than adults, or long-term users over the course of decades.

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However scary all of that may sound, though, general consensus seems to be that these risks are tiny, and if encountered, often easily tackled by changing dosages. Even the Army’s health warning on CBD vaping described pure CBD oil, on its own, as relatively safe.

How safe is it to vape CBD?

In theory, nothing about vaping—which just heats a tincture of a substance at high temperatures to create a vapor to inhale—should change the risk profile of CBD. However, Michelle Peace, a toxicologist and vaping expert at Virginia Commonwealth University, does note that, “when you inhale something as opposed to eating something,” the way many other CBD products are consumed, “you do have to be careful about dosing because inhalation is a much more efficient way to get drugs into the system and be active.”

Cannabis industry companies tend to claim vaping CBD makes the same dose about four times more potent, although Peace notes that there are as of yet no real and conclusive studies on this subject. Regardless, that could clearly lead people prone to CBD side effects or drug-drug interactions to face increased risks of negative effects, which could explain some emergency room visits. This risk is easily addressed by exercising due caution about dosing, as one would (or should) with any other substance.

The nature of vapes, however, could introduce a few new risks to CBD usage, even if the process of vaping doesn’t. Earlier this year, a study on vapes at Johns Hopkins University found that, while heating, some of their coils—the metal bits used to heat tinctures—likely leech notable amounts of heavy metals like chromium and nickel into the vapor users eventually inhale. “What is the long-term impact of inhaling these particulate metals?” Peace says. “We don’t fully understand that yet.”

How safe are CBD oils themselves?

Vape oils are also poorly regulated, which has resulted in frequent reports of items sold as, say, pure nicotine that are actually adulterated with known toxic substances. Some of these substances, like the buttery flavoring agent diacetyl, are perfectly safe to, say, eat, but when heated in a vape and inhaled, can cause serious lung irritation. CBD vape oils are no different: A 2017 study of 10 such products found that seven misrepresented the dosage of CBD found within them and two contained THC, the other well-known cannabinoid in cannabis that often has oppositional effects to CBD. This may speak to mischaracterizations of the source of the CBD in a vape product: isolated and purified CBD extracts or a concoction made of whole plant cannabis that had a high CBD:THC ratio. Some scientists worry that vaporizing as opposed to burning and smoking whole cannabis materials can lead to unique complications, failing to break down a waxy material from the plant’s leaves, which can then build up in a vaper’s lungs and cause irritation. Peace notes that her lab has also studied some CBD products and found worrying items in some of them that were not announced on the box. In the products they evaluated, she says, “rarely have we found that there has been much truth in advertising.”

Health officials seem to consider this rampant, hidden adulteration the greatest risk associated with vaping CBD as opposed to consuming it in any other form. The Army’s health warning called out the risk of adulteration with synthetic cannabinoids and high concentrations of THC in these products in particular as the likely cause of many, if not all, of the CBD vaping illnesses it saw. And that could be a huge problem for vapers: Peace notes that usually her advice would be for people interested in vaping CBD to just be conscious consumers, reading product labels and consulting their doctors about dosing and possible drug-drug interactions. However, no one has a master list of questionable brands, or a good sense of how to spot them. Peace notes that even some seemingly legitimate retailers may be selling bad tinctures.

As such, conscious and cautious consumption is almost impossible. Nor is it possible for users to make a real and rational gauge of risk, given uncertainty about the scale of adulteration in the industry. The only real solution to this risk—common to all forms of vaping—would be greater regulation of the industry. But with no signs of that in the offing, users can only approach vaping of CBD or any other substance with a degree of caution and a knowledge of the risks involved.

Vaping CBD – the Benefits and Side Effects

Vaping CBD has been on the rise in popularity this past year. And it’s already a booming industry, globally. People around the globe are jumping on the CBD train, and companies are coming out with all the newest and funnest ways to take it.

Traditionally we’d have to smoke a joint to get a good hit of CBD, but that’s no longer necessary. Now, you can take CBD orally in the form of capsules or edibles. It can used on your skin, and Vaping CBD, even with tanks and coils, has never been easier.

However, do we really know what CBD is? Should we be worried about what it will do to our bodies if we vape it? Keep reading to get the 2020 version of the truth about vaping CBD and whether or not it’s safe.

What is CBD?

CBD (known as cannabidiol in the science world) is a cannabinoid found in cannabis and hemp plants. It was only discovered a few decades ago, and has been under the microscope for even fewer years.

It has recently become very popular because of its promising effects on our bodies. CBD is processed by a system in our bodies called the Endocannabinoid System (ECS) which is responsible for regulating many of the most important functions in our bodies such as sleep, hormonal balances, and memory.

When a person takes CBD, it can affect them in many different ways and in varying amounts of time depending on how much they take, the type of CBD product they use, and how they take it. Since there are so many options out there, one can easily tailor their CBD routine to their own needs and preferences.


One of the most common questions regarding CBD is: ‘Does CBD make you high?’, and there is only one answer to it across the board: ‘absolutely not’. CBD is a cannabinoid and is found in cannabis and hemp plants. Without THC it can’t make you high.

THC, on the other hand, is well-known across the globe for the infamous high it gives you. Unfortunately, CBD and THC are often lumped together since they’re both from cannabis and hemp plants, but they are very different.

In fact, CBD and THC are processed by entirely different ECS receptors in different areas of our bodies. CBD is processed by CB2 receptors which are located throughout our bodies, and THC is processed by CB1 receptors which are found in our brains.

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The main difference between CBD and THC is that one makes you high and the other gives you a load of other benefits without the high. Now that you know this, you should totally go and spread the CBD knowledge and join the global CBD education movement!

How Safe is Vaping CBD?

One of the US’ favorite ways of taking CBD is by vaping CBD. This is due to many different reasons, and these are a few:

  • It is the fastest-acting way of taking CBD
  • It’s so easy and fast to vape throughout the day
  • There are so many flavours and CBD strengths available
  • There are THC-free options and options with THC available

With that said, as more and more people begin to take up vaping CBD, there are questions being raised about the safety of vaping CBD. Many attribute this to the big vaping scandal that has been going on recently, resulting in many people either stopping vaping or companies such as Apple putting a ban on everything vaporizer related.

Is it actually safe to vape CBD? This is a very particular question, as it carries so much weight behind it; and the answer varies depending on where you are, how you obtain the CBD vaporizer and vape liquid, and other things. Let’s dive into it.


There was recently (August, 2019) a very impactful lawsuit against a CBD vaporizer company. Erin Gilbert had used CBD by vaping it, and shortly after began to experience life-threatening side effects to the degree of respiratory failure down and the amputation of both her legs due to blood clots.

She purchased a mango-flavoured CBD vape pen and used it during the day. It was very apparent that the CBD vape pen had caused her these unimaginable consequences, but why? What happened that caused this to happen?

Erin Gilbert

Erin Gilbert lived in the U.S. Virgin Islands, which is where she purchased and used the CBD vape pen, and where the sale and manufacturing of CBD is still illegal. This leads investigators to believe that she purchased this vape pen from an under-the-radar seller.

Since CBD products (CBD vapes included) aren’t even legal in the U.S. Virgin Islands, there is even less chance that the CBD vape Gilbert used was tested, monitored, and/or approved by any health or food and drug regulation agency. This is where the simple act of vaping CBD became so dangerous.

CBD has never been known to cause any side effects other than nausea, headaches, diarrhea, or vomiting, and even these side effects are rare. This takes us to analyzing the other ingredients used in the CBD vape liquid Gilbert consumed.

Counterfeited CBD Dangers

Counterfeited CBD products, including the one Erin Gilbert used, have been found to contain a number of different substances used as a carrier oil. These ingredients include vitamin E acetate, which is what Gilbert’s hospitalization was traced to.

Vitamin E Acetate

Vitamin E acetate, among other substances, can be incredibly harmful to our bodies when vaporized, and the fact that counterfeit or low-end vaporizer companies are using it in their vape liquids is a huge issue at the moment due to cases such as Gilbert’s.

Does this make vaping CBD dangerous? Not as a whole. There is a large difference between the type of CBD vaporizer that Gilbert used and the CBD vaporizer being used in countries where it is legal. The UK and the USA are legal CBD countries.

Points to Consider

What does this show us? Here are some incredibly important points to consider in order to make sure you’ll be safe when vaping CBD:

  • Always make sure vaping CBD is legal and monitored in your country.
  • Make no exceptions. If you want to buy a CBD vape product, always make sure you purchase it from a well-known and reputable brand.
  • Read the third-party lab tests! Reputable CBD brands offer third-party lab results. You should always check them for CBD and THC content. Also additional information regarding the ingredients in the CBD vape liquid.
  • Go easy if you’re new to CBD. By starting out at a low CBD dosage you will ensure that your body gets used to CBD and you could avoid some of the pesky side effects it may cause.

Benefits of Vaping CBD

Though there are some scary cases such as Erin Gilbert’s case, vaping CBD isn’t actually bad for you. There is a super high number of people using CBD vapes all over the world, and the vast majority of them have benefited from it rather than suffered because of it.

  • Our bodies process CBD the quickest when inhaled in vapor form.
  • Anxiety, depression, insomnia or trouble sleeping, can be eased with CBD.
  • CBD can help manage pain caused by conditions or diseases such as multiple sclerosis, Parkinson’s, or arthritis; and may even be of use when treating neurological pain.
  • It has been known to reduce inflammation and pain caused by it, and to serve as a treatment for inflamed muscles or joints.
  • Cannabinoids may help people regain their appetite or help people with disorders such as ARFID (avoidant/restrictive food intake disorder).

CBD has a plethora of benefits for our bodies. The fact is that you most likely never experience any side effects. Especially if you make sure to stay away from vitamin E acetate.

Side Effects of Vaping CBD

Side effects are well covered above. Does vaping good CBD have side effects? Should you experience any at all? Here’s some info:

  • Side effects of vaping good, legal CBD are the same side effects associated with taking CBD in any form. These include:
    • Nausea
    • Vomiting
    • Diarrhea
    • Dizziness
    • Stomachache

    Alternatives to Vaping CBD

    As the CBD market grows, there are more and more ways of taking CBD that are available to the public. Is vaping CBD the only option? Not at all! There are so many other ways of taking CBD that are almost as quick-acting and efficient as vaping CBD! Here are some:

    • CBD sprays and CBD oils are a great way to take CBD orally. They are very potent and have long-lasting effects.
    • Aromatherapy products from CBD are perfect for taking an indirect way. You still reap its benefits.
    • CBD crystals and CBD isolates added to any food or beverage. One can have a lot of liberty over how much CBD they take, and when they take it. are a perfect alternative for people who don’t like the taste of CBD.


    You don’t have to be afraid of vaping CBD. As long as you make sure to stay safe by following safety tips you’re fine. You can see that vaping CBD is just one option. You can skip out on the vaping scene and still have options available to you.